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To sustain health, virtually every tissue in the body must regenerate itself regularly. Having adequate supplies of all the nucleic acid bases may be one of the most significant limiting factors on whether tissue can express its greatest capacity for regeneration and self-repair. Any tissue, to regenerate, requires the ability to make DNA and RNA to support the process of making new cells. Providing readily absorbed and assimilated nucleotides can be one of the most powerful ways to assist any tissue in repairing and renewing itself.
Several wound-healing studies have assessed the effects of supplemental nucleic acids on wound healing. Compared to the control group, those receiving the supplements showed more rapid healing, greater tensile strength of the skin, and significantly reduced scarring.
Some of the tiniest organs in the body have the most profound effects on our health and well-being. These are the endocrine glands that secrete minute amounts of hormones into the blood without which every function of the body can suffer. The pituitary gland The adrenal glands The thymus gland The thyroid gland The salivary glands
The intestinal lining replaces* all of its cells every seven days. Only a single layer thick, this lining is highly dependent on a sufficient supply of nucleic acids to completely regenerate itself every week. If nutritional support is inadequate, defective regeneration of the intestinal mucosal lining impairs the enzymatic stages of digestion, which can lead to a vicious cycle of deteriorating digestion and nutritional status. Upon administration of supplemental nucleotides, the appearance of the intestinal lining greatly improved, with regeneration of the height of the absorptive intestinal villi. In addition, the enzyme content and function of the Intestinal lining also greatly improved, permitting the animals to recover* and thrive.
AMPPs have enormous importance for human health because they kill microorganisms (bacteria, viruses, fungi, protozoa) on the interfaces between the external and internal environment of the body (intestine, lung, skin, urinary tract) and protect the circulatory system from the penetration of microbes (Yu & comp. 2010). AMPP regulates immune response and slows dangerous inflammatory responses that are dangerous to the body.
An additional finding in individuals who received nucleotide supplementation was an improvement in their blood lipid profiles*. In particular, the individuals receiving added nucleic acids were found to have higher HDL cholesterol levels, the cholesterol fraction that protects against cardiovascular disease the higher the level.
Studies in young laboratory animals have assessed the effects of supplementing DNA and RNA elements. Compared to control animals, the supplemented animals grew, developed, and increased muscle mass at a greater rate. Other vital proteins were also built more readily in the treated animals. The intestinal lining in particular matured more robustly in the supplemented animals. Research thus far indicates that the tremendous need for nucleic acids in growth and development is strongly beneficially supported by supplementing these vital nutritional elements.
Cellular immunity refers in particular to immune cells that have the role of identifying cells in the body that have become abnormal, so that the abnormal cells can be removed. The main cellular changes sought through the cellular immune system are the development of cancer cells or various types of intracellular infection. The goal of the cellular immune system is to eliminate cancer cells or infected cells before they can become established in the body to cause serious illness. The main effectors of cellular immunity are cells that arise in the thymus gland. These cells are often called T cells for their thymus derivation, of which there are several types with varying functions. A special type of T cell called a cytotoxic T cell has the role of finding and sticking to abnormal cells, then releasing substances that selectively digest and clear the renegade cells.
Many studies in animals and humans have found a dramatic improvement in memory function with nucleic acid supplementation. Whether it is the ability to remember the right pathway to get through a maze for a prize of cheese, or to remember facts and figures, giving supplements of DNA and RNA elements has significantly increased performance. Perhaps most dramatically, one researcher has focused on giving nucleic acids to persons with dementia. Even with advanced cases, if he went to high enough delivery levels to his patients, in almost every case memory improvement was very significant. The doctor reported that even in advanced cases of dementia dramatic memory recovery occurred if high enough levels of nucleic acids were given*.
It is perhaps functional nucleic acid deficiency that limits our potential for healthy longevity more than any other single factor of all the interventions that have ever been attempted to increase the life span of mammals, no method ever studied has been more powerful for mammalian life extension than nucleic acid supplementation. Compared to other techniques that have increased the longevity of experimental animals by up to 50%, administering nucleic acids has doubled and even tripled the usual maximum life span.
ATP stands for adenosine triphosphate, perhaps the most important of all the nucleic acid derivatives in the body. Its effects are so powerful and essential to cellular function, a description of its unique properties warrants special attention. ATP is the fundamental currency of every cell in the body. Virtually every activity in the body that requires energy uses ATP as the source of power. Whether the function is building complex molecules from building blocks, maintaining the electric potential of cell membranes, or allowing muscle fibers to contract for mobility, speed, and strength, it is ATP that provides the electrochemical fuel. The oxygenating effects of nucleotide supplementation combined with a supply of ATP are likely to be additive and even synergistic in helping cells throughout the body achieve higher energy potentials and more ideal energy balances.
There are two fundamental ways ATP is generated in the body, one very efficient and one very wasteful. Efficient ATP production occurs through aerobic metabolism in the mitochondria, tiny organs or organelles within the cell that burn fuels like fat and glucose to generate ATP. Aerobic means that oxygen is used to completely burn a fuel for maximum ATP production. For example, the complete combustion of a single glucose molecule to carbon dioxide and water yields a rich harvest of 36 molecules of ATP. As nucleotides boost cellular oxygen delivery, already making ATP production more efficient, the ATP has an ideal environment for further boosting cellular energy conditions; thus all the desirable ATP effects are likely to be even more potent. The oxygenating effects of nucleotide supplementation combined with a supply of ATP are likely to be additive and even synergistic in helping cells throughout the body achieve higher energy potentials and more ideal energy balances.
ATP is the primary fuel that drives learning, memory, and concentration functions*.
The cyclic contraction of cardiac muscle is highly ATP-intensive and thrives on aerobic metabolism. The combined oxygenation and ATP delivery effects of DNA/RNA formulas provide the heart with an enhanced energy supply for efficient function*.
Skeletal Muscle also requires abundant quantities of ATP for muscular contraction. Supplemental ATP has been described as an explosive performance enhancer. Especially, if given two other nutrient supporters of muscle function, creatine monohydrate and creatine pyruvate, muscle endurance, performance, and recovery can be significantly boosted*.
ATP administration has been shown to have numerous beneficial effects on lung function, particularly the delicate lining membranes of the airways and alveoli. In some conditions, the blood pressure in the vessels in the lungs can rise too high, a condition known as pulmonary hypertension. ATP binds to the lining of the pulmonary vessels and stimulates a cascade of events that cause the blood vessels to relax and lower the pressure. Cystic fibrosis is one of the most common inherited genetic diseases. Impaired water and electrolyte secretion from the bronchial lining results in thick secretions that block the bronchial tubes and result in recurring infections. ATP has been found to increase electrolyte and water secretion with improved clearance of secretions, offering hope of a new and useful intervention in this often aggressively progressive condition.
In human tissue studies, the increase of ATP* and adenosine has been found to induce the smooth muscle relaxation that is essential for erectile function. In diabetic men, erectile dysfunction is common through several mechanisms. The erectile tissue of diabetic men is especially sensitive to the smooth muscle relaxation effects of ATP, offering them a hopeful avenue of recovery of erectile function.
Under conditions of metabolic stress, such as depriving a tissue of oxygen through reduced blood supply, a rapid and massive depletion of ATP within cells occurs. Regen has been described as a ~natural defense system~ to protect the tissues from the effects of severe oxygen deprivation. These protective effects include improved function of energy-generating mitochondria, better electrolyte transport*, increased ATP within cells, reduced oxygen consumption, and improved function of messenger molecules within the cells. Stress is a condition in which there is a generalized reduction of blood flow and oxygenation to tissues below that required for their function. If stress is sustained, the prolonged tension from internal or external stressors may cause various physical manifestations – e.g., asthma, back pain, arrhythmias, fatigue, headaches, irritable bowel syndrome, ulcers, and suppress the immune system”. It can raise blood pressure, increase the risk of heart attack and stroke, increase vulnerability to anxiety and depression, contribute to infertility, and hasten the aging process.
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